Affiliation:
1. Laboratory for Vascular Medicine and Stem Cell Biology, Department of Physiology, Medical Research Institute, School of Medicine, Pusan National University, Yangsan 50612, Republic of Korea
2. Convergence Stem Cell Research Center, Pusan National University, Yangsan 50612, Republic of Korea
Abstract
Within the human body, the intricate network of blood vessels plays a pivotal role in transporting nutrients and oxygen and maintaining homeostasis. Bioprinting is an innovative technology with the potential to revolutionize this field by constructing complex multicellular structures. This technique offers the advantage of depositing individual cells, growth factors, and biochemical signals, thereby facilitating the growth of functional blood vessels. Despite the challenges in fabricating vascularized constructs, bioprinting has emerged as an advance in organ engineering. The continuous evolution of bioprinting technology and biomaterial knowledge provides an avenue to overcome the hurdles associated with vascularized tissue fabrication. This article provides an overview of the biofabrication process used to create vascular and vascularized constructs. It delves into the various techniques used in vascular engineering, including extrusion-, droplet-, and laser-based bioprinting methods. Integrating these techniques offers the prospect of crafting artificial blood vessels with remarkable precision and functionality. Therefore, the potential impact of bioprinting in vascular engineering is significant. With technological advances, it holds promise in revolutionizing organ transplantation, tissue engineering, and regenerative medicine. By mimicking the natural complexity of blood vessels, bioprinting brings us one step closer to engineering organs with functional vasculature, ushering in a new era of medical advancement.
Funder
Korean Fund for Regenerative Medicine
Subject
Biomedical Engineering,Biomaterials
Reference255 articles.
1. Critical appraisal of surgical revascularization for critical limb ischemia;Conte;J. Vasc. Surg.,2013
2. MR Angiography for Aortic Diseases;Garg;Magn. Reson. Imaging Clin. N. Am.,2023
3. Prophylactic intravenous tranexamic acid and thromboembolism in non-cardiac surgery: A systematic review, meta-analysis and trial sequential analysis;Tsan;Anaesthesia,2023
4. Tuohy, M.C., Hillman, E.M.C., Marshall, R., and Agalliu, D. (2023). The age-dependent immune response to ischemic stroke. Curr. Opin. Neurobiol., 78.
5. A review of current status of cell-based therapies for aortic aneurysms;Mutsuga;Inflamm. Regen.,2023
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献