Recent Progress on Microfluidics Integrated with Fiber-Optic Sensors for On-Site Detection

Author:

Wang Weibin1,Xia Ling1,Xiao Xiaohua1,Li Gongke1ORCID

Affiliation:

1. School of Chemistry, Sun Yat-sen University, Guangzhou 510006, China

Abstract

This review introduces a micro-integrated device of microfluidics and fiber-optic sensors for on-site detection, which can detect certain or several specific components or their amounts in different samples within a relatively short time. Fiber-optics with micron core diameters can be easily coated and functionalized, thus allowing sensors to be integrated with microfluidics to separate, enrich, and measure samples in a micro-device. Compared to traditional laboratory equipment, this integrated device exhibits natural advantages in size, speed, cost, portability, and operability, making it more suitable for on-site detection. In this review, the various optical detection methods used in this integrated device are introduced, including Raman, ultraviolet–visible, fluorescence, and surface plasmon resonance detections. It also provides a detailed overview of the on-site detection applications of this integrated device for biological analysis, food safety, and environmental monitoring. Lastly, this review addresses the prospects for the future development of microfluidics integrated with fiber-optic sensors.

Funder

the State Key Program of National Natural Science of China

the National Natural Science Foundation of China

Guangdong Basic and Applied Basic Research Foundation

Publisher

MDPI AG

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