Circulating Biomarkers of Thyroid Cancer: An Appraisal-Reference-Cited by-同舟云学术

Circulating Biomarkers of Thyroid Cancer: An Appraisal

Published:2025-02-26 Issue:5 Volume:14 Page:1582
ISSN:2077-0383
Container-title:Journal of Clinical Medicine
language:en
Short-container-title:JCM

Author:

Codrich Marta¹^ORCID,Biasotto Alessia¹²,D’Aurizio Federica¹²^ORCID

Affiliation:

1. Department of Medicine (DMED), University of Udine, 33100 Udine, Italy

2. Institute of Clinical Pathology, Academic Hospital “Santa Maria della Misericordia”, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy

Abstract

Thyroid cancer is the most prevalent endocrine cancer. The prognosis depends on the type and stage at diagnosis. Thyroid cancer treatments involve surgery, possibly followed by additional therapeutic options such as hormone therapy, radiation therapy, targeted therapy and chemotherapy. Besides the well-known thyroid tumor biomarkers, new circulating biomarkers are now emerging. Advances in genomic, transcriptomic and proteomic technologies have allowed the development of novel tumor biomarkers. This review explores the current literature data to critically analyze the benefits and limitations of routinely measured circulating biomarkers for the diagnosis and monitoring of thyroid cancer. The review also sheds light on new circulating biomarkers, focusing on the challenges of their use in the clinical management of thyroid cancer, underlining the need for the identification of a new generation of circulating biomarkers.

Publisher

MDPI AG

Link

https://www.mdpi.com/2077-0383/14/5/1582/pdf

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