Vitamins in the Pathogenesis of Prostate Cancer: Implications for Prevention and Therapeutic Support

Author:

Królikowska Kinga1,Kiślak Jakub1,Orywal Karolina2ORCID,Zajkowska Monika3ORCID

Affiliation:

1. Department of Population Medicine and Lifestyle Diseases Prevention, The Faculty of Medicine, Medical University of Białystok, 15-269 Białystok, Poland

2. Department of Biochemical Diagnostics, Medical University of Bialystok, Waszyngtona 15A St., 15-269 Bialystok, Poland

3. Department of Neurodegeneration Diagnostics, Medical University of Bialystok, Waszyngtona 15A St., 15-269 Bialystok, Poland

Abstract

Prostate cancer is one of the most common malignancies in men and represents a major challenge for modern medicine. In recent years, there has been growing interest in the role of vitamins in the pathogenesis of this disease, as well as their potential impact on prevention and supportive treatment. Studies conducted so far suggest that certain vitamins may exhibit antioxidant and anti-inflammatory properties, thus supporting the immune response, which may influence cancer risk and treatment efficacy. This article aims to present the current state of knowledge on the role of vitamins in prostate cancer, focusing on their potential importance both in prevention and as an adjunct to therapy. Vitamins A, D, E, C, and B-group compounds may influence prostate cancer development and progression through mechanisms such as antioxidant activity, regulation of cell proliferation, apoptosis, and immune modulation. Despite promising insights from basic research, clinical studies remain inconclusive, and the effects of vitamin supplementation depend on factors like dosage, form, and individual variability. Therefore, a balanced diet rich in natural vitamins is recommended, while further research is needed to clarify their therapeutic and preventive roles in prostate cancer.

Publisher

MDPI AG

Reference68 articles.

1. Recent Patterns and Trends in Global Prostate Cancer Incidence and Mortality: An Update;Schafer;Eur. Urol.,2025

2. Comparative study of cancer profiles between 2020 and 2022 using global cancer statistics (GLOBOCAN);Cao;J. Natl. Cancer Cent.,2024

3. Global Cancer Observatory-Europe, Ferlay, J., Ervik, M., Lam, F., Laversanne, M., Colombet, M., Mery, L., Piñeros, M., Znaor, A., and Soerjomataram, I. (2024). Global Cancer Observatory: Cancer Today, International Agency for Research on Cancer. Available online: https://gco.iarc.who.int/today.

4. Epidemiology and Prevention of Prostate Cancer;Gandaglia;Eur. Urol. Oncol.,2021

5. Adeloye, D., David, R.A., Aderemi, A.V., Iseolorunkanmi, A., Oyedokun, A., Iweala, E.E.J., Omoregbe, N., and Ayo, C.K. (2016). An Estimate of the Incidence of Prostate Cancer in Africa: A Systematic Review and Meta-Analysis. PLoS ONE, 11.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.7亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2025 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3