Contrast Agents during Pregnancy: Pros and Cons When Really Needed-Reference-Cited by-同舟云学术

Contrast Agents during Pregnancy: Pros and Cons When Really Needed

Published:2022-12-12 Issue:24 Volume:19 Page:16699
ISSN:1660-4601
Container-title:International Journal of Environmental Research and Public Health
language:en
Short-container-title:IJERPH

Author:

Perelli Federica¹,Turrini Irene²^ORCID,Giorgi Maria Gabriella²,Renda Irene³,Vidiri Annalisa⁴,Straface Gianluca⁵,Scatena Elisa²,D’Indinosante Marco²,Marchi Laura²,Giusti Marco¹,Oliva Antonio⁶^ORCID,Grassi Simone⁶^ORCID,De Luca Carmen⁷,Catania Francesco⁸,Vizzielli Giuseppe⁹^ORCID,Restaino Stefano⁹^ORCID,Gullo Giuseppe¹⁰^ORCID,Eleftheriou Georgios¹¹,Mattei Alberto¹,Signore Fabrizio¹²¹³,Lanzone Antonio⁴¹⁴,Scambia Giovanni⁴¹⁵,Cavaliere Anna Franca⁴¹⁶

Affiliation:

1. Azienda USL Toscana Centro, Gynecology and Obstetric Department, Santa Maria Annunziata Hospital, 50012 Florence, Italy

2. Azienda USL Toscana Centro, Gynecology and Obstetric Department, Santo Stefano Hospital, 59100 Prato, Italy

3. Division of Obstetrics and Gynecology, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, 50134 Florence, Italy

4. School of Medicine, Catholic University of the Sacred Hearth, 00168 Rome, Italy

5. Obstetrics and Gynecology Unit, Policlinico Abano Terme, 35031 Abano Terme, Italy

6. Department of Health Surveillance and Bioethics, Section of Legal Medicine, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy

7. Teratology Information Service, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy

8. Department of Obstetrics and Gynecology, Ospedale “Santa Maria Alla Gruccia”, 52025 Montevarchi, Italy

9. Department of Medicinal Area (DAME) Clinic of Obstetrics and Gynecology, Santa Maria della Misericordia Hospital, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy

10. IVF Public Center, Azienda Ospedaliera Ospedali Riuniti (AOOR) Villa Sofia Cervello, University of Palermo, 90146 Palermo, Italy

11. Poison Control Center and Teratology Information Service, Hospital Papa Giovanni XIII, 24127 Bergamo, Italy

12. Obstetrics and Gynecology Unit, Santo Eugenio Hospital, 00144 Rome, Italy

13. School of Medicine, Unicamillus University Rome, 00131 Rome, Italy

14. Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy

15. Division of Gynecologic Oncology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy

16. Division of Gynecology and Obstetrics Fatebenefratelli Isola Tiberina, 00186 Rome, Italy

Abstract

Many clinical conditions require radiological diagnostic exams based on the emission of different kinds of energy and the use of contrast agents, such as computerized tomography (CT), positron emission tomography (PET), magnetic resonance (MR), ultrasound (US), and X-ray imaging. Pregnant patients who should be submitted for diagnostic examinations with contrast agents represent a group of patients with whom it is necessary to consider both maternal and fetal effects. Radiological examinations use different types of contrast media, the most used and studied are represented by iodinate contrast agents, gadolinium, fluorodeoxyglucose, gastrographin, bariumsulfate, and nanobubbles used in contrast-enhanced ultrasound (CEUS). The present paper reports the available data about each contrast agent and its effect related to the mother and fetus. This review aims to clarify the clinical practices to follow in cases where a radiodiagnostic examination with a contrast medium is indicated to be performed on a pregnant patient.

Publisher

MDPI AG

Link

https://www.mdpi.com/1660-4601/19/24/16699/pdf

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