Optofluidic Tweezers: Efficient and Versatile Micro/Nano-Manipulation Tools

Author:

Zhu Yuchen1234,You Minmin5,Shi Yuzhi1234,Huang Haiyang1234,Wei Zeyong1234,He Tao1234ORCID,Xiong Sha6,Wang Zhanshan1234,Cheng Xinbin1234

Affiliation:

1. Institute of Precision Optical Engineering, School of Physics Science and Engineering, Tongji University, Shanghai 200092, China

2. MOE Key Laboratory of Advanced Micro-Structured Materials, Shanghai 200092, China

3. Shanghai Institute of Intelligent Science and Technology, Tongji University, Shanghai 200092, China

4. Shanghai Frontiers Science Center of Digital Optics, Shanghai 200092, China

5. National Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai 200240, China

6. School of Automation, Central South University, Changsha 410083, China

Abstract

Optical tweezers (OTs) can transfer light momentum to particles, achieving the precise manipulation of particles through optical forces. Due to the properties of non-contact and precise control, OTs have provided a gateway for exploring the mysteries behind nonlinear optics, soft-condensed-matter physics, molecular biology, and analytical chemistry. In recent years, OTs have been combined with microfluidic chips to overcome their limitations in, for instance, speed and efficiency, creating a technology known as “optofluidic tweezers.” This paper describes static OTs briefly first. Next, we overview recent developments in optofluidic tweezers, summarizing advancements in capture, manipulation, sorting, and measurement based on different technologies. The focus is on various kinds of optofluidic tweezers, such as holographic optical tweezers, photonic-crystal optical tweezers, and waveguide optical tweezers. Moreover, there is a continuing trend of combining optofluidic tweezers with other techniques to achieve greater functionality, such as antigen–antibody interactions and Raman tweezers. We conclude by summarizing the main challenges and future directions in this research field.

Funder

National Natural Science Foundation of China

Shanghai Pilot Program for Basic Research, Science and Technology Commission of Shanghai Municipality

“Shu Guang” project supported by Shanghai Municipal Education Commission and Shanghai Education

Project funded by China Postdoctoral Science Foundation

Natural Science Foundation of Hunan Province

Fundamental Research Funds for the Central Universities

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Mechanical Engineering,Control and Systems Engineering

Reference152 articles.

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