Emerging Role of Nuclear Medicine in Prostate Cancer: Current State and Future Perspectives

Author:

Volpe Fabio1ORCID,Nappi Carmela1,Piscopo Leandra1ORCID,Zampella Emilia1ORCID,Mainolfi Ciro Gabriele1,Ponsiglione Andrea1ORCID,Imbriaco Massimo1ORCID,Cuocolo Alberto1ORCID,Klain Michele1ORCID

Affiliation:

1. Department of Advanced Biomedical Sciences, University of Naples Federico II, 80138 Naples, Italy

Abstract

Prostate cancer is the most frequent epithelial neoplasia after skin cancer in men starting from 50 years and prostate-specific antigen (PSA) dosage can be used as an early screening tool. Prostate cancer imaging includes several radiological modalities, ranging from ultrasonography, computed tomography (CT), and magnetic resonance to nuclear medicine hybrid techniques such as single-photon emission computed tomography (SPECT)/CT and positron emission tomography (PET)/CT. Innovation in radiopharmaceutical compounds has introduced specific tracers with diagnostic and therapeutic indications, opening the horizons to targeted and very effective clinical care for patients with prostate cancer. The aim of the present review is to illustrate the current knowledge and future perspectives of nuclear medicine, including stand-alone diagnostic techniques and theragnostic approaches, in the clinical management of patients with prostate cancer from initial staging to advanced disease.

Publisher

MDPI AG

Subject

Cancer Research,Oncology

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Alpha emitter isotopes and PSMA ligands: the near future therapeutic prospective for castration-resistant prostate cancer;European Journal of Nuclear Medicine and Molecular Imaging;2023-12-23

2. Metastatic castration-resistant prostate cancer therapy: the quest for the perfect molecule;European Journal of Nuclear Medicine and Molecular Imaging;2023-11-21

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