A 22-G or a 25-G Needle: Which One to Use in the Diagnostics of Solid Pancreatic Lesions? A Systematic Review and Meta-Analysis

Author:

Nawacki Łukasz1ORCID,Gorczyca-Głowacka Iwona1ORCID,Zieliński Paweł1,Znamirowski Przemysław1ORCID,Kozłowska-Geller Monika1,Ciba-Stemplewska Agnieszka1ORCID,Kołomańska Magdalena1

Affiliation:

1. Collegium Medicum, The Jan Kochanowski University in Kielce, Aleja IX Wieków Kielc 19A, 25-317 Kielce, Poland

Abstract

With the 12th highest incidence and a common late diagnostic at advanced stages, neoadjuvant therapies for pancreatic cancer are important, but they require a confirmed diagnosis. Being a diagnostic standard, the clarification of the clinical relevance of needle gauges is needed, as larger ones may retrieve more tissue for diagnostics, but may also increase the risk of complications. We performed a meta-analysis to compare the efficiency of the most commonly used 22-G and 25-G needles for EUS guided biopsy in solid pancreatic lesions. The MEDLINE (via PubMed), Embase, Cochrane (CENTRAL), and Scopus databases were searched with “EUS”, “needle”, “FNA”, “pancreas”, “prospective”, “22G”, and “25G” keywords. Mixed effects were assessed in the model, with a mean of 86% and a 95% confidence interval. Fourteen prospective studies that compared the efficiency of 22-G and 25-G biopsy needles in 508 and 524 lesions, respectively, were analyzed, along with 332 specimens biopsied using both needle sizes. The groups did not significantly differ in the outcomes. A low degree of heterogeneity was observed overall, except for specimen adequacy. Moreover, 22-G and 25-G needles have comparable safety and efficacy for focal pancreatic lesion biopsies without a high risk of complications.

Publisher

MDPI AG

Reference40 articles.

1. Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes;McGuigan;World J. Gastroenterol.,2018

2. Pancreatic cancer: A review of epidemiology, trend, and risk factors;Hu;World J. Gastroenterol.,2021

3. He, W., Goodkind, D., and Kowal, P. (2016). An Aging World: 2015, US Government Publishing Office. US Census Bureau Report Number P95/16.

4. Pancreatic cancer epidemiology: Understanding the role of lifestyle and inherited risk factors;Klein;Nat. Rev. Gastroenterol. Hepatol.,2021

5. Smoking and pancreatic cancer incidence: A pooled analysis of 10 population-based cohort studies in Japan;Koyanagi;Cancer Epidemiol. Biomark. Prev.,2019

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