The Long Non-Coding RNA ANRIL in Cancers-Reference-Cited by-同舟云学术

The Long Non-Coding RNA ANRIL in Cancers

Published:2023-08-17 Issue:16 Volume:15 Page:4160
ISSN:2072-6694
Container-title:Cancers
language:en
Short-container-title:Cancers

Author:

Sanchez Aymeric¹,Lhuillier Julien¹,Grosjean Guillaume²^ORCID,Ayadi Lilia¹,Maenner Sylvain¹^ORCID

Affiliation:

1. CNRS, Université de Lorraine, IMoPA, F-54000 Nancy, France

2. SATT Sayens, F-54000 Nancy, France

Abstract

ANRIL (Antisense Noncoding RNA in the INK4 Locus), a long non-coding RNA encoded in the human chromosome 9p21 region, is a critical factor for regulating gene expression by interacting with multiple proteins and miRNAs. It has been found to play important roles in various cellular processes, including cell cycle control and proliferation. Dysregulation of ANRIL has been associated with several diseases like cancers and cardiovascular diseases, for instance. Understanding the oncogenic role of ANRIL and its potential as a diagnostic and prognostic biomarker in cancer is crucial. This review provides insights into the regulatory mechanisms and oncogenic significance of the 9p21 locus and ANRIL in cancer.

Funder

CNRS-UL and SATT SAYENS

Publisher

MDPI AG

Subject

Cancer Research,Oncology

Link

https://www.mdpi.com/2072-6694/15/16/4160/pdf

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