Improved Prediction of Ovarian Cancer Using Ensemble Classifier and Shaply Explainable AI

Author:

Abuzinadah Nihal1ORCID,Kumar Posa Sarath2,Alarfaj Aisha Ahmed3,Alabdulqader Ebtisam Abdullah4,Umer Muhammad5ORCID,Kim Tai-Hoon6,Alsubai Shtwai7ORCID,Ashraf Imran8ORCID

Affiliation:

1. Faculty of Computer Science and Information Technology, King Abdulaziz University, P.O. Box 80200, Jeddah 21589, Saudi Arabia

2. Department of Information Science, University of Arkansas at Little Rock, Little Rock, AR 72204, USA

3. Department of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia

4. Department of Information Technology, College of Computer and Information Sciences, King Saud University, Riyadh 12372, Saudi Arabia

5. Department of Computer Science & Information Technology, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan

6. School of Electrical and Computer Engineering, Yeosu Campus, Chonnam National University, 50, Daehak-ro, Yeosu-si 59626, Jeollanam-do, Republic of Korea

7. Department of Computer Science, College of Computer Engineering and Sciences, Prince Sattam bin Abdulaziz University, P.O. Box 151, Al-Kharj 11942, Saudi Arabia

8. Department of Information and Communication Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea

Abstract

The importance of detecting and preventing ovarian cancer is of utmost significance for women’s overall health and wellness. Referred to as the “silent killer,” ovarian cancer exhibits inconspicuous symptoms during its initial phases, posing a challenge for timely identification. Identification of ovarian cancer during its advanced stages significantly diminishes the likelihood of effective treatment and survival. Regular screenings, such as pelvic exams, ultrasound, and blood tests for specific biomarkers, are essential tools for detecting the disease in its early, more treatable stages. This research makes use of the Soochow University ovarian cancer dataset, containing 50 features for the accurate detection of ovarian cancer. The proposed predictive model makes use of a stacked ensemble model, merging the strengths of bagging and boosting classifiers, and aims to enhance predictive accuracy and reliability. This combination harnesses the benefits of variance reduction and improved generalization, contributing to superior ovarian cancer prediction outcomes. The proposed model gives 96.87% accuracy, which is currently the highest model result obtained on this dataset so far using all features. Moreover, the outcomes are elucidated utilizing the explainable artificial intelligence method referred to as SHAPly. The excellence of the suggested model is demonstrated through a comparison of its performance with that of other cutting-edge models.

Funder

Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia

Publisher

MDPI AG

Subject

Cancer Research,Oncology

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