Abstract
Oncogenic transformation drives adaptive changes in a growing tumor that affect the cellular organization of cancerous cells, resulting in the loss of specialized cellular functions in the polarized compartmentalization of cells. The resulting altered metabolic and morphological patterns are used clinically as diagnostic markers. This review recapitulates the known functions of actin, microtubules and the γ-tubulin meshwork in orchestrating cell metabolism and functional cellular asymmetry.
Funder
the Swedish Cancer Society
the Swedish Childhood Cancer Foundation
the Skane University Hospital in Malmö Cancer Research fund
Cited by
1 articles.
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1. Centrosome Movements Are TUBG1-Dependent;International Journal of Molecular Sciences;2023-08-24