Minimally-Invasive Secondary Cytoreduction in Recurrent Ovarian Cancer

Author:

Certelli Camilla12,Russo Silvio Andrea12,Palmieri Luca12ORCID,Foresta Aniello12,Pedone Anchora Luigi1ORCID,Vargiu Virginia1ORCID,Santullo Francesco3,Fagotti Anna1,Scambia Giovanni1,Gallotta Valerio1

Affiliation:

1. Gynecologic Oncology Unit, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy

2. Institute of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore, 00168 Rome, Italy

3. Surgical Unit of Peritoneum and Retroperitoneum, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy

Abstract

The role of secondary cytoreductive surgery (SCS) in the treatment of recurrent ovarian cancer (ROC) has been widely increased in recent years, especially in trying to improve the quality of life of these patients by utilising a minimally-invasive (MI) approach. However, surgery in previously-treated patients may be challenging, and patient selection and surgical planning are crucial. Unfortunately, at the moment, validated criteria to select patients for MI-SCS are not reported, and no predictors of its feasibility are currently available, probably due to the vast heterogeneity of recurrence patterns. The aim of this narrative review is to describe the role of secondary cytoreductive surgery and, in particular, minimally-invasive procedures, in ROC, analyzing patient selection, outcomes, criticisms, and future perspectives.

Publisher

MDPI AG

Subject

Cancer Research,Oncology

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