The Genetic Analysis and Clinical Therapy in Lung Cancer: Current Advances and Future Directions-Reference-Cited by-同舟云学术

The Genetic Analysis and Clinical Therapy in Lung Cancer: Current Advances and Future Directions

Published:2024-08-19 Issue:16 Volume:16 Page:2882
ISSN:2072-6694
Container-title:Cancers
language:en
Short-container-title:Cancers

Author:

Rina Angela¹²^ORCID,Maffeo Debora¹³,Minnai Francesca⁴,Esposito Martina⁴^ORCID,Palmieri Maria¹³^ORCID,Serio Viola Bianca¹³^ORCID,Rosati Diletta¹³,Mari Francesca²³^ORCID,Frullanti Elisa¹³^ORCID,Colombo Francesca⁴^ORCID

Affiliation:

1. Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy

2. UOC Laboratorio di Assistenza e Ricerca Traslazionale, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy

3. Cancer Genomics and Systems Biology Laboratory, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy

4. Institute of Biomedical Technologies, National Research Council, 20054 Segrate, Italy

Abstract

Lung cancer, including both non-small cell lung cancer and small cell lung cancer, remains the leading cause of cancer-related mortality worldwide, representing 18% of the total cancer deaths in 2020. Many patients are identified already at an advanced stage with metastatic disease and have a worsening prognosis. Recent advances in the genetic understanding of lung cancer have opened new avenues for personalized treatments and targeted therapies. This review examines the latest discoveries in the genetics of lung cancer, discusses key biomarkers, and analyzes current clinical therapies based on this genetic information. It will conclude with a discussion of future prospects and potential research directions.

Publisher

MDPI AG

Link

https://www.mdpi.com/2072-6694/16/16/2882/pdf

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