Author:
Казеко Л.А.,Захарова В.А.,Субботко И.Л.,Бенеш Ю.Д.
Abstract
Цель. Оценить характер экспрессии тканевого ингибитора матриксных металлопротеиназ-2 (ТИМП-2) в биоптатах здоровой слизистой оболочки полости рта.Материалы и методы. Забор биопсийного материала был выполнен у 30 пациентов. Биоптаты здоровой слизистой оболочки были получены во время дентальной имплантации.Результаты. Эпителиальная и стромальная экспрессия ТИМП-2 наблюдалась во всех проанализированных случаях. Умеренная экспрессия преобладала в эпителии, низкая экспрессия – в строме.Заключение. Здоровая слизистая оболочка полости рта характеризуется низкой и умеренной экспрессией ТИМП-2.
Purpose. To evaluate features of the expression of tissue inhibitor of matrix metalloproteinases-2 (TIMP-2) in biopsies of healthy oral mucosa.Methods. Sampling of biopsy material was performed in 30 patients. Biopsies of healthy oral mucosa were obtained during the dental implantation procedure.Results. Epithelial and stromal expression of TIMP-2 was observed in all analyzed cases. Moderate expression prevailed in the epithelium, low expression in the stroma.Conclusion. Healthy oral mucosa is characterized by low and moderate expression of TIMP-2.
Publisher
Professionals Publications
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