Understanding and Managing Methotrexate Nephrotoxicity-Reference-Cited by-同舟云学术

Understanding and Managing Methotrexate Nephrotoxicity

Published:2006-06-01 Issue:6 Volume:11 Page:694-703
ISSN:1083-7159
Container-title:The Oncologist
language:en
Short-container-title:

Author:

Widemann Brigitte C.¹,Adamson Peter C.²

Affiliation:

1. a Pediatric Oncology Branch, National Cancer Institute, Bethesda, Maryland, USA

2. b Division of Clinical Pharmacology & Therapeutics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

Abstract

Learning Objectives After completing this course, the reader will be able to: Discuss the pharmacology of methotrexate.Describe the current incidence and presentation of high-dose methotrexate-induced renal dysfunction.Discuss conventional and investigational treatment approaches to high-dose methotrexate-induced renal dysfunction. Access and take the CME test online and receive 1 AMA PRA category 1 credit at CME.TheOncologist.com

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1634/theoncologist.11-6-694

Reference79 articles.

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2. High-dose methotrexate (NSC-740) and citrovorum factor (NSC-3590) rescue: background and rationale;Djerassi;Cancer Chemother Rep,1975

3. The pharmacology and clinical use of methotrexate;Jolivet;N Engl J Med,1983

4. Methotrexate in juvenile rheumatoid arthritis. Evidence of age dependent pharmacokinetics;Albertioni;Eur J Clin Pharmacol,1995

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