Drug Development for Hepatocellular Carcinoma: Knowing the Past Helps to Understand the Future

Author:

Chan Stephen L.1

Affiliation:

1. State Key Laboratory in Oncology in South China, Sir Y.K. Pao Center for Cancer, Department of Clinical Oncology, Hong Kong Cancer Institute and Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, People's Republic of China

Abstract

Hepatocellular carcinoma (HCC) is a highly complicated disease characterized by comorbid cirrhosis and disease heterogeneity. Given multiple failures in the past, we need to learn from previous experiences and generate novel ideas to increase the chance of success. More effort and patience should be exercised in the selection of a homogeneous patient population and identification of predictive markers during drug development for HCC.

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

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