Malignant Peripheral Nerve Sheath Tumors

Author:

Farid Mohamad1,Demicco Elizabeth G.1,Garcia Roberto1,Ahn Linda1,Merola Pamela R.1,Cioffi Angela1,Maki Robert G.1

Affiliation:

1. Tisch Cancer Institute, Mount Sinai School of Medicine, New York, New York, USA

Abstract

Learning Objectives Explain the characteristics and treatment of malignant peripheral nerve sheath tumors, both in relation to neurofibromatosis type I and otherwise. Cite the unique challenges in optimal management of malignant peripheral nerve sheath tumors. Appraise the large amount of new data surrounding the potential molecular drivers, possible targets for therapy in this disease.

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

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3. Mouse models of tumor development in neurofibromatosis type 1;Cichowski;Science,1999

4. Neurofibromas in NF1: Schwann cell origin and role of tumor environment;Zhu;Science,2002

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