1. First Department of Medicine (T.H., T.U., J.K., A.T., M.K.) Toyama Medical and Pharmaceutical University Toyama, 930-0194, Japan
2. Department of Medicine (K.E., P.M.S., J.M.O.) Division of Endocrinology and Metabolism and Whittier Diabetes Institute University of California, San Diego La Jolla, California 92093
3. Veterans Administration Research Service (J.M.O.) San Diego, California 92161