VCAM1 Is Induced in Ovarian Theca and Stromal Cells in a Mouse Model of Androgen Excess

Author:

Candelaria Nicholes R1ORCID,Padmanabhan Achuth1,Stossi Fabio12,Ljungberg M Cecilia34,Shelly Katharine E5,Pew Braden K1,Solis Minerva1,Rossano Ayane M1,McAllister Jan M6,Wu Sheng7,Richards JoAnne S1

Affiliation:

1. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas

2. Integrated Microscopy Core, Baylor College of Medicine, Houston, Texas

3. Department of Pediatrics, Baylor College of Medicine, Houston, Texas

4. Jan and Dan Duncan Neurologic Research Institute at Texas Children’s Hospital, Houston, Texas

5. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas

6. Department of Pathology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania

7. Department of Pediatrics and Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland

Funder

National Institute of Child Health and Human Development

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Institute of Diabetes and Digestive and Kidney Diseases

Division of Cancer Prevention, National Cancer Institute

Cancer Prevention and Research Institute of Texas

NIH Office of the Director

Publisher

The Endocrine Society

Subject

Endocrinology

Reference85 articles.

1. Theca: the forgotten cell of the ovarian follicle;Young;Reproduction,2010

2. Ovarian follicular theca cell recruitment, differentiation, and impact on fertility: 2017 update;Richards;Endocr Rev,2018

3. van Beek AP, Cantineau AE. Ovarian hyperthecosis. Available at: https://www.uptodate.com/contents/ovarian-hyperthecosis. Accessed 14 February 2018.

4. Ontogeny of the ovary in polycystic ovary syndrome;Dumesic;Fertil Steril,2013

5. Lineage specification of ovarian theca cells requires multicellular interactions via oocyte and granulosa cells;Liu;Nat Commun,2015

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