Substitution of Cysteine for Selenocysteine in the Catalytic Center of Type III Iodothyronine Deiodinase Reduces Catalytic Efficiency and Alters Substrate Preference
Author:
Affiliation:
1. Department of Internal Medicine, Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands
Publisher
The Endocrine Society
Subject
Endocrinology
Link
http://academic.oup.com/endo/article-pdf/144/6/2505/9303049/endo2505.pdf
Reference68 articles.
1. Iodothyronine deiodinases.;Köhrle;Methods Enzymol,2002
2. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases.;Bianco;Endocr Rev,2002
3. The deiodinase family of selenoproteins.;St. Germain;Thyroid,1997
4. Pathways of thyroid hormone metabolism.;Visser;Acta Med Austriaca,1996
5. Characteristics of type III iodothyronine deiodinase.;Visser;Acta Med Austriaca,1992
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