Affiliation:
1. Department of Medical Psychology (S.E., M.S.), 45122 Essen, Germany
2. Division of Endocrinology, Department of Medicine (S.H., D.K., K.M., O.E.J.), University of Essen, 45122 Essen, Germany
3. Division of Angiology, Department of Medicine (A.H.Ö.), Hospital Schwabing, 80804 Munich, Germany
Abstract
Abstract
Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by chronic anovulation and hyperandrogenism. PCOS is one of the leading causes of infertility and manifests with hirsutism, acne, and obesity. To investigate its impact on health-related quality of life and sexuality, 50 women with PCOS and 50 controls were evaluated with standardized questionnaires (36-item short-form health survey, symptom checklist revised, and life satisfaction questionnaire). The impact of hirsutism, obesity, and infertility was assessed using five-point rating scales, and sexual satisfaction was analyzed with visual analog scales. Patients showed greater psychological disturbances on the symptom checklist revised dimensions, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, aggression, and psychoticism, along with a lower degree of life satisfaction in the life satisfaction questionnaire scales health, self, and sex. Health-related quality of life measured with the 36-item short-form health survey revealed significantly decreased scores for physical role function, bodily pain, vitality, social function, emotional role function, and mental health in patients with PCOS. Although patients had the same partner status and frequency of sexual intercourse, they were significantly less satisfied with their sex life and found themselves less attractive. Most of the differences were not affected by correction for body weight. In conclusion, PCOS causes a major reduction in the quality of life and severely limits sexual satisfaction.
Subject
Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism
Reference31 articles.
1. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study.;Knochenhauer;J Clin Endocrinol Metab,1998
2. A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain.;Asuncion;J Clin Endocrinol Metab,2000
3. Current concepts in the polycystic ovary syndrome.;Dunaif;Annu Rev Med,2001
4. Molecular progress in infertility: polycystic ovary syndrome.;Legro;Fertil Steril,2002
5. Insulin resistance in polycystic ovary syndrome: progress and paradoxes.;Venkatesan;Recent Prog Horm Res,2001