A Novel Type of P450c17 Lacking the Lyase Activity Is Responsible for C21-Steroid Biosynthesis in the Fish Ovary and Head Kidney-Reference-Cited by-同舟云学术

A Novel Type of P450c17 Lacking the Lyase Activity Is Responsible for C21-Steroid Biosynthesis in the Fish Ovary and Head Kidney

Published:2007-09-01 Issue:9 Volume:148 Page:4282-4291
ISSN:0013-7227
Container-title:Endocrinology
language:en
Short-container-title:

Author:

Zhou Lin-Yan¹²,Wang De-Shou¹³⁴,Kobayashi Tohru¹⁵,Yano Akihiro¹,Paul-Prasanth Bindhu¹³,Suzuki Aya¹³,Sakai Fumie¹³,Nagahama Yoshitaka¹²³

Affiliation:

1. Laboratory of Reproductive Biology (L.-Y.Z., D.-S.W., T.K., A.Y., B.P.-P., A.S., F.S., Y.N.), Graduate University for Advanced Studies, Okazaki 444-8585, Japan

2. National Institute for Basic Biology, and School of Life Science (L.-Y.Z., Y.N.), Graduate University for Advanced Studies, Okazaki 444-8585, Japan

3. SORST (D.-S.W., B.P.-P., A.S., F.S., Y.N.), Japan Science and Technology Corp.

4. School of Life Science (D.-S.W.), Southwest University, 400715 Chongqing, People’s Republic of China

5. National Research Institute of Aquaculture (T.K.), Tamaki, Mie 519-0423, Japan

Publisher

The Endocrine Society

Subject

Endocrinology

Link

http://academic.oup.com/endo/article-pdf/148/9/4282/10715058/endo4282.pdf

Reference41 articles.

1. Cytochrome P450c17 (steroid 17α-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues.;Chung;Proc Natl Acad Sci USA,1987

2. Androgen biosynthesis from cholesterol to DHEA.;Miller;Mol Cell Endocrinol,2002

3. Minireview: regulation of steroidogenesis by electron transfer.;Miller;Endocrinology,2005

4. Regulation of 17, 20 lyase activity by cytochrome b5 and by serine phosphorylation of P450c17.;Pandey;J Biol Chem,2005

5. Serine phosphorylation of human P450c17 increases 17, 20-lyase activity: implications for adrenarche and the polycystic ovary syndrome.;Zhang;Proc Natl Acad Sci USA,1995

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