Formation of a Human β-Cell Population within Pancreatic Islets Is Set Early in Life

Author:

Gregg Brigid E.1,Moore Patrick C.1,Demozay Damien1,Hall Ben A.1,Li Mei2,Husain Aliya2,Wright Amy J.3,Atkinson Mark A.3,Rhodes Christopher J.1

Affiliation:

1. The Kovler Diabetes Center (B.E.G., P.C.M., D.D., B.A.H., C.J.R.), Chicago, Illinois 60637

2. Department of Medicine,and Department of Pathology (M.L., A.H.), University of Chicago, Chicago, Illinois 60637

3. Department of Pathology, Immunology, and Laboratory Medicine (A.J.W., M.A.A.), University of Florida College of Medicine, Gainesville, Florida 32607

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference40 articles.

1. Type-2 diabetes; a matter of β-cell life and death?;Rhodes;Science,2005

2. The β-cell lesion in type 2 diabetes: there has to be a primary functional abnormality.;Kahn;Diabetologia,2009

3. Pathogenesis of type 2 diabetes mellitus.;Leahy;Arch Med Res,2005

4. The islands of Langerhans in 19 cases of obesity.;Ogilvie;J Pathol,1933

5. Adaptation of islets of Langerhans to pregnancy: β-cell growth, enhanced insulin secretion and the role of lactogenic hormones.;Sorenson;Horm Metab Res,1997

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