Affiliation:
1. Broadstreet HEOR Vancouver British Columbia Canada
2. Organon Jersey City New Jersey USA
Abstract
AbstractObjectiveTo identify and synthesize epidemiologic data for preterm labour (PTL) and preterm birth (PTB).MethodsA systematic search, with protocol registered in PROSPERO, was implemented in MEDLINE and EMBASE and supplemented by web‐based and grey literature searches. Observational, population‐based studies in the United States, Canada, United Kingdom, France, Germany, Spain, and Italy, published in English between 2012 and 2022 were considered for inclusion. Estimates by country were reported and stratified by gestational age, birth plurality, and race/ethnicity, data permitting.ResultsTen publications and nine grey literature reports were included. Epidemiologic estimates of PTL were reported for the United Kingdom and France: PTL was diagnosed in 2.2% of pregnancies and preceded 50% of PTBs. PTB rates were reported for the United States, Canada, United Kingdom, France, and Spain. Among live births in these countries, annual PTB incidence ranged from 5.9% (Spain, 2020) to 10.2% (United States, 2019). Most countries reported the PTB incidence by gestational age; reports by birth plurality or race/ethnicity were scarce. PTB rates for Germany or Italy were not identified.ConclusionsWhile PTBs were well‐reported overall and by gestational age, how rates varied by plurality, race/ethnicity and etiology is unclear. Epidemiologic estimates for PTL, a leading cause of PTB, were rarely reported in the literature. Population‐based research is needed to understand the burden of PTL and for decision making regarding the management of this condition.
Reference55 articles.
1. Practice Bulletin No. 171: Management of Preterm Labor
2. National Institute for Health & Care Excellence. Preterm labour and birth. Accessed April 29 2022 2015.https://www.nice.org.uk/guidance/ng25/resources/preterm-labour-and-birth-pdf-1837333576645
3. The Society of Obstetricians and Gynaecologists of Canada. Preterm labour.2004. Accessed May 24 2022.https://www.pregnancyinfo.ca/birth/special-considerations/preterm-labour/
4. Global burden of preterm birth