Identification of novel candidate compounds targeting TrkB to induce apoptosis in neuroblastoma

Author:

Nakamura Yohko1,Suganami Akiko2,Fukuda Mayu1,Hasan Md. Kamrul1,Yokochi Tomoki1,Takatori Atsushi1,Satoh Shunpei1,Hoshino Tyuji3,Tamura Yutaka2,Nakagawara Akira1

Affiliation:

1. Division of Biochemistry and Innovative Cancer Therapeutics; Chiba Cancer Center Research Institute; Chiba 260-8717 Japan

2. Department of Bioinformatics; Graduate School of Medicine; Chiba University; Chiba 260-8670 Japan

3. Department of Physical Chemistry; Graduate School of Pharmaceutical Sciences; Chiba University; Chiba 260-8675 Japan

Funder

Ministry of Health, Labour and Welfare for Third Term Comprehensive Control Research for Cancer

JSPS KAKENHI

Takeda Science Foundation

Publisher

Wiley

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Oncology

Reference28 articles.

1. Neuroblastoma: biological insights into a clinical enigma;Brodeur;Nat. Rev. Cancer,2003

2. The NGF story and neuroblastoma;Nakagawara;Med. Pediatr. Oncol.,1998

3. Molecular basis of spontaneous regression of neuroblastoma: role of neurotrophic signals and genetic abnormalities;Nakagawara;Hum. Cell,1998

4. Trk receptor tyrosine kinases: a bridge between cancer and neural development;Nakagawara;Cancer Lett.,2001

5. Identification and characterization of a 500-kb homozygously deleted region at 1p36.2-p36.3 in a neuroblastoma cell line;Ohira;Oncogene,2000

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