Preoperative diagnosis of ureteral medial deviations secondary to deep endometriosis using transvaginal ultrasound examinations: Can we predict the need for ureterolysis during laparoscopic surgery?

Author:

Carfagna Pietro1,De Cicco Nardone Alessandra1ORCID,Benvenga Greta1,Nardone Fiorenzo De Cicco1,Greco Pierfrancesco2,Campolo Federica1,Pafundi Pia Clara3,Alesi Maria Vittoria2,Testa Antonia Carla12,Scambia Giovanni12,Ianieri Manuel Maria124

Affiliation:

1. Fondazione Policlinico Universitario A. Gemelli, IRCCS, UOC Ginecologia Oncologica, Dipartimento per la salute della Donna e del Bambino e della Salute Pubblica Rome Italy

2. Università Cattolica del Sacro Cuore Rome Italy

3. Faculty of Epidemiology and Biostatistics—GEMELLI GENERATOR Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy

4. Gynecology and Breast Care Center, Mater Olbia Hospital Olbia Italy

Abstract

AbstractObjectiveTo evaluate ureteral involvement using transvaginal sonography (TVS) regarding the distortion of the course of the ureters caused by deep endometriosis (DE), which can facilitate predicting the need for ureterolysis during surgery, even in the absence of ureteral stenosis or dilatation.MethodsThis is a single‐center, observational, retrospective pilot study of 88 consecutive patients who later underwent surgery for DE that used ultrasound preoperative diagnosis of ureteral medial deviation of one or both ureters between January 2019 and January 2022. At TVS, the course of the ureter was considered medialized if, in longitudinal and transversal section, any distance was detectable between the ureter and the cervix at the point where the ureter crosses the uterine artery. The primary end point was to determine sensitivity, specificity, and positive and negative predictive values of “ureteral medial deviation” diagnosed using TVS, in order to predict the need for ureterolysis.ResultsOur series included 88 women with a median age of 39 (interquartile range 33–43) years. Ureteral medialization showed a relatively low false‐positive rate (10.9%), with a specificity of 89.1% (95% confidence interval [CI] 81.4%–96.7%) and a sensitivity of 86.6% (95% CI 80.3%–92.9%), along with a high positive predictive value of 93.3% (95% CI 88.4%–98.1%), and a lower negative predictive value of 79.1% (95% CI 69.8%–88.5%), respectively.ConclusionsThis study introduced a new ultrasound sign with a high degree of accuracy to predict ureterolysis and this may have positive implications in the management and surgical planning of patients with ureteral endometriosis.

Publisher

Wiley

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