Pathology of inflammatory diseases of the nervous system: Human disease versus animal models
Author:
Affiliation:
1. Institut fur HirnforschungMedical University of Vienna Wien Austria
Publisher
Wiley
Subject
Cellular and Molecular Neuroscience,Neurology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/glia.23726
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1. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
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3. Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain
4. Astrocyte scar formation aids central nervous system axon regeneration
5. Clonal Expansions of Cd8+ T Cells Dominate the T Cell Infiltrate in Active Multiple Sclerosis Lesions as Shown by Micromanipulation and Single Cell Polymerase Chain Reaction
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