Late‐Stage Modification of Aminoglycoside Antibiotics Overcomes Bacterial Resistance Mediated by APH(3’) Kinases

Author:

Bastian Andreas A.123,Bastian Maria2,Jäger Manuel1,Loznik Mark453,Warszawik Eliza M.46,Yang Xintong45,Tahiri Nabil1,Fodran Peter1,Witte Martin D.1,Thoma Anne53,Köhler Jens5ORCID,Minnaard Adriaan J.1,Herrmann Andreas453ORCID

Affiliation:

1. Department of Chemical Biology Stratingh Institute for Chemistry Nijenborgh 7 9747 AG Groningen (The Netherlands

2. AGILeBiotics B.V. De Mudden 14 9747 AV Groningen (The Netherlands

3. Institute for Technical and Macromolecular Chemistry RWTH Aachen University Worringerweg 2 52074 Aachen Germany

4. Department of Polymer Chemistry Zernike Institute for Advanced Materials Nijenborgh 4 9747 AG Groningen (The Netherlands

5. DWI – Leibniz Institute for Interactive Materials Forckenbeckstr. 50 52056 Aachen Germany

6. Department of Biomedical Engineering-FB40 W. J. Kolff Institute-FB41 Antonius Deusinglaan 1 9713 AV Groningen (The Netherlands

Funder

European Research Council

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Reference58 articles.

1.  

2. World Health Organization. Antimicrobial resistance: global report on surveillance.2014 http://www.who.int/drugresistance/documents/surveillancereport/en/;

3. Antibiotic resistance: The last resort

4. Emerging Infectious Diseases: a 10-Year Perspective from the National Institute of Allergy and Infectious Diseases

5.  

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