Discovery of Homobivalent Bitopic Ligands of the Cannabinoid CB 2 Receptor**-Reference-Cited by-同舟云学术

Discovery of Homobivalent Bitopic Ligands of the Cannabinoid CB 2 Receptor**

Published:2020-11-09 Issue:68 Volume:26 Page:15839-15842
ISSN:0947-6539
Container-title:Chemistry – A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Morales Paula¹^ORCID,Navarro Gemma²^ORCID,Gómez‐Autet Marc³,Redondo Laura¹,Fernández‐Ruiz Javier⁴^ORCID,Pérez‐Benito Laura³⁵^ORCID,Cordomí Arnau³^ORCID,Pardo Leonardo³^ORCID,Franco Rafael²⁶^ORCID,Jagerovic Nadine¹^ORCID

Affiliation:

1. Medicinal Chemistry Institute Spanish Research Council Madrid Spain

2. Department of Biochemistry and Physiology, CIBERNED Faculty of Pharmacy and Food Sciences Universitat de Barcelona Barcelona Spain

3. Laboratory of Computational Medicine, Biostatistics Unit Faculty of Medicine Universitat Autónoma de Barcelona Barcelona Spain

4. Department of Biochemistry and Molecular Biology, CIBERNED, IRYCIS Faculty of Medicine Universidad Complutense de Madrid Madrid Spain

5. Present address: Computational Chemistry Janssen Research & Development, Janssen Pharmaceutica N.V. Belgium

6. Department of Biochemistry and Molecular Biology, CIBERNED School of Chemistry Universitat de Barcelona Barcelona Spain

Funder

Ministerio de Ciencia, Innovación y Universidades

Consejo Superior de Investigaciones Científicas

Comunidad de Madrid

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.202003389

Reference36 articles.

1. Mechanisms of signalling and biased agonism in G protein-coupled receptors

2. Allosteric Modulation of GPCRs: New Insights and Potential Utility for Treatment of Schizophrenia and Other CNS Disorders

3. Bridging the gap: bitopic ligands of G-protein-coupled receptors

4. Molecular Alliance-From Orthosteric and Allosteric Ligands to Dualsteric/Bitopic Agonists at G Protein Coupled Receptors

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