Enhanced CHO Clone Screening: Application of Targeted Locus Amplification and Next‐Generation Sequencing Technologies for Cell Line Development-Reference-Cited by-同舟云学术

Enhanced CHO Clone Screening: Application of Targeted Locus Amplification and Next‐Generation Sequencing Technologies for Cell Line Development

Published:2019-05-15 Issue:7 Volume:14 Page:1800371
ISSN:1860-6768
Container-title:Biotechnology Journal
language:en
Short-container-title:Biotechnol. J.

Author:

Aeschlimann Samuel H.¹,Graf Christian²,Mayilo Dmytro¹,Lindecker Hélène¹,Urda Lorena¹,Kappes Nora¹,Burr Alicia Leone¹,Simonis Marieke³,Splinter Erik³,Min Max³,Laux Holger¹

Affiliation:

1. Novartis Institutes for BioMedical Research, Integrated Biologics Profiling UnitCH‐4002 Basel Switzerland

2. Novartis Technical R&D, Technical Development BiosimilarsHexal AG, Keltenring 1+3 82041 Oberhaching Germany

3. Cergentis B.VYalelaan 62 3584 CM Utrecht The Netherlands

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/biot.201800371

Reference61 articles.

1. Mammalian cell protein expression for biopharmaceutical production

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4. 25 years of recombinant proteins from reactor-grown cells — Where do we go from here?

5. Industrialization of mAb production technology: The bioprocessing industry at a crossroads

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