Clinical Translation of Inorganic Nanoparticles and Engineered Living Materials for Cancer Therapy

Author:

Gandarias Lucía12,Faivre Damien1ORCID

Affiliation:

1. Aix-Marseille Université CEA CNRS BIAM 13115 Saint-Paul-lez-Durance France

2. Dpto. de Electricidad y Electrónica Universidad del País Vasco (UPV/EHU) 48940 Leioa Spain

Abstract

AbstractA wide range of particle‐based nano‐ to microsystems is currently under investigation for potential use in personalized nanomedicine. However, only a small fraction of these innovations is likely to make it to clinical use. In this concept article, we start by discussing the potential applications of inorganic nanoparticles in cancer treatment and diagnosis, and shed light on the challenges they must overcome to become clinically available. In the second part, we focus on engineered living materials, which have begun to revolutionize the way medical interventions could be performed. Finally, we share our insights and opinions to explain why, despite significant advancements in research on these technologies, their translation to clinical practice remains limited.

Funder

Institut National de la Santé et de la Recherche Médicale

Eusko Jaurlaritza

Publisher

Wiley

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