Affiliation:
1. Electrochemical Power Sources Division CSIR-Central Electrochemical Research Institute Karaikudi 630003, Sivagangai District Tamil Nadu India
2. Faculty of Chemistry University of Wrocław 14 Fryderyka Joliot-Curie 50-383 Wrocław Poland
Abstract
Abstractπ‐Activation of alkynyl precursors possessing an endogenous carbon nucleophile is one of the imperative topics in homogeneous gold catalysis as it offers Csp3‐Csp2 and Csp2‐Csp2 linked carbocycles. However, the exo‐dig and endo‐dig cyclization modes unlocks the possibility of both small and large rings respectively, thereby losing regioselectivity. Nevertheless, several gold‐catalyzed carbocyclizations which permits one isomer by controlling or avoiding the formation of other went largely unnoticed. Hence, this review is an attempt to summarize such approaches reported from early 2000’s to till date along with our viewpoint on contributing parameters for regioselectivity. This review covers only unimolecular reactions with classifications primarily based on the type of endogenous nucleophiles such as silyloxyenols, enamides/enamines, benzenoids, heteroaromatics and alkyls/alkenyls. From an application perspective, these reactions are significant in total synthesis and materials science. Therefore, those reactions that finds application in natural product synthesis and π‐functional materials are highlighted in appropriate places.
Funder
Narodowa Agencja Wymiany Akademickiej
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献