Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents

Author:

Goedeke Leigh1,Bates Jamie2,Vatner Daniel F.1,Perry Rachel J.1,Wang Ting2,Ramirez Ricardo2,Li Li2,Ellis Matthew W.3,Zhang Dongyan1,Wong Kari E.4,Beysen Carine5,Cline Gary W.1,Ray Adrian S.2,Shulman Gerald I.136

Affiliation:

1. Department of Internal Medicine; Yale University School of Medicine; New Haven CT

2. Gilead Sciences Inc.; Foster City CA

3. Department of Cellular and Molecular Physiology; Yale University School of Medicine; New Haven CT

4. Metabolon Inc.; Morrisville NC

5. Independent Researcher; San Mateo CA

6. Howard Hughes Medical Institute; Yale University School of Medicine; New Haven CT

Funder

National Institutes of Health

National Institute of Diabetes and Digestive and Kidney Diseases

Gilead Sciences

Publisher

Wiley

Subject

Hepatology

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