Flavonoids improve the stability and function of <scp>P23H</scp> rhodopsin slowing down the progression of retinitis pigmentosa in mice-Reference-Cited by-同舟云学术

Flavonoids improve the stability and function of P23H rhodopsin slowing down the progression of retinitis pigmentosa in mice

Published:2022-02-15 Issue:4 Volume:100 Page:1063-1083
ISSN:0360-4012
Container-title:Journal of Neuroscience Research
language:en
Short-container-title:J of Neuroscience Research

Author:

Ortega Joseph Thomas¹,Parmar Tanu¹,Carmena‐Bargueño Miguel²,Pérez‐Sánchez Horacio²,Jastrzebska Beata¹

Affiliation:

1. Department of Pharmacology, Cleveland Center for Membrane and Structural Biology, School of Medicine Case Western Reserve University Cleveland Ohio USA

2. Structural Bioinformatics and High Performance Computing Research Group (BIO‐HPC) UCAM Universidad Católica de Murcia Guadalupe Spain

Funder

National Eye Institute

Universidad de Málaga

Research Council, Rutgers, The State University of New Jersey

Ministerio de Economía y Competitividad

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jnr.25021

Reference47 articles.

1. Ablation of the Proapoptotic Genes Chop or Ask1 Does Not Prevent or Delay Loss of Visual Function in a P23H Transgenic Mouse Model of Retinitis Pigmentosa

2. The role of the ER stress-response protein PERK in rhodopsin retinitis pigmentosa

3. The molecular and cellular basis of rhodopsin retinitis pigmentosa reveals potential strategies for therapy

4. A Small Chaperone Improves Folding and Routing of Rhodopsin Mutants Linked to Inherited Blindness

5. A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration

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