Visible‐Light‐Driven Sulfonamidation of Arylazo Sulfonesthrough One‐Pot Multicomponent Reaction

Abstract

AbstractSulfonamide is one of the most important structures in organic chemistry due to its frequent appearance in natural products as well as pharmaceuticals. This study reports a visible‐light‐promoted strategy for synthesis of sulfonamides from arylazo sulfones. One‐pot tri‐component reactions were conducted using arylazo sulfones, DABSO, and amines in the presence of CuBr2 as a coupling catalyst under irradiation with blue LEDs to prepare various sulfonamides in good yields under mild conditions. This method could be used effectively to produce a variety of useful sulfonamides.