Transition Metal‐Catalyzed Carboamination of Alkenes and Allenes: Recent Progress

Abstract

AbstractVicinal carboamination of carbon‐carbon multiple bonds is a highly reliable and efficient practical strategy for the quick preparation of valuable and diverse amine derivatives starting from simple synthons. The last decade has witnessed numerous practical methods employing transition metal carboamination approaches of alkenes and allenes for the synthesis of these N‐bearing entities. Driven by the renaissance of transition metal catalysis, inter‐and intramolecular carboamination of alkenes and allenes comprising concomitant C−N and C−C bond formation has been studied extensively. Interestingly, existing reviews describing developments on carboamination of alkenes are mostly reaction path specific and confined to a particular metal catalyst. Whereas, guiding congregation of literature on carboamination of allene is not documented. In this review, different conceptual approaches will be discussed and examples from the recent literature will be presented with special focus to the detailed reaction mechanism.