Molecular Dynamics Simulations of Ligand-Induced Flap Conformational Changes in Cathepsin-D-A Comparative Study
Author:
Affiliation:
1. Molecular Modelling and Drug Design Research Group; School of Health Sciences; University of KwaZulu-Natal; Westville, Durban 4000 South Africa
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference86 articles.
1. Revised 2.3-A structure of porcine pepsin-Evidence for a flexible subdomain;Abadzapatero;Proteins Struct Funct Genet,1990
2. Relationship between the expression of various markers and prognostic factors in breast cancer;Anim;Acta Histochem,2005
3. Crystal structures of native and inhibited forms of human cathepsin D: Implications for lysosomal targeting and drug design;Baldwin;Proc Natl Acad Sci USA,1993
4. Modulation of proliferation and chemosensitivity by procathepsin D and its peptides in ovarian cancer;Bazzett;Gynecol Oncol,1999
5. Molecular-dynamics with coupling to an external bath;Berendsen;J Chem Phys,1984
Cited by 13 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Flap Dynamics in Pepsin-Like Aspartic Proteases: A Computational Perspective Using Plasmepsin-II and BACE-1 as Model Systems;Journal of Chemical Information and Modeling;2022-02-09
2. pH-Dependent Structural Dynamics of Cathepsin D-Family Aspartic Peptidase of Clonorchis sinensis;Pathogens;2021-09-02
3. In vitro and computational studies on the antiglycation activity of compounds isolated from antidiabetic Tetracera alnifolia stem bark;Journal of Biomolecular Structure and Dynamics;2021-06-07
4. Dehydroacetic Acid-Phenylhydrazone as a Potential Inhibitor for Wild-Type HIV-1 Protease: Structural, DFT, Molecular Dynamics, 3D QSAR and ADMET Characteristics;IRAN J CHEM CHEM ENG;2021
5. Flap dynamics in pepsin-like aspartic proteases: a computational perspective using Plasmepsin-II and BACE-1 as model systems;2020-04-27
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3