1. Université de Lorraine, INSERM, Centre d'Investigations Cliniques Plurithématique 1433, INSERM U1116 CHRU de Nancy, F‐CRIN INI‐CRCT Nancy France
2. Department of Medicine University of Michigan School of Medicine Ann Arbor Michigan USA
3. Robertson Centre for Biostatistics and Clinical Trials, University of Glasgow and National Heart & Lung Institute, London, UK