Immunomodulatory Effects of Lenvatinib Plus Anti–Programmed Cell Death Protein 1 in Mice and Rationale for Patient Enrichment in Hepatocellular Carcinoma

Author:

Torrens Laura12ORCID,Montironi Carla12ORCID,Puigvehí Marc13ORCID,Mesropian Agavni2ORCID,Leslie Jack4ORCID,Haber Philipp K.1,Maeda Miho1,Balaseviciute Ugne2ORCID,Willoughby Catherine E.2ORCID,Abril‐Fornaguera Jordi2ORCID,Piqué‐Gili Marta2ORCID,Torres‐Martín Miguel12ORCID,Peix Judit2ORCID,Geh Daniel4ORCID,Ramon‐Gil Erik4ORCID,Saberi Behnam1,Friedman Scott L.1ORCID,Mann Derek A.4ORCID,Sia Daniela1ORCID,Llovet Josep M.125ORCID

Affiliation:

1. Mount Sinai Liver Cancer Program Division of Liver Diseases Tisch Cancer InstituteIcahn School of Medicine at Mount Sinai New York NY

2. Translational Research in Hepatic Oncology Liver Unit Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)‐Hospital ClínicUniversitat De Barcelona Barcelona Spain

3. Hepatology Section Gastroenterology Department Parc de Salut MarIMIM (Hospital del Mar Medical Research Institute) Barcelona Spain

4. Newcastle Fibrosis Research Group Biosciences InstituteNewcastle University Newcastle upon Tyne United Kingdom

5. Institució Catalana De Recerca i Estudis Avançats Barcelona Spain

Funder

Cancer Research UK

Universitat de Barcelona

European Association for the Study of the Liver

Deutsche Forschungsgemeinschaft

Samuel Waxman Cancer Research Foundation

Ministerio de Ciencia e Innovación

U.S. Department of Defense

Asociación Española para el Estudio del Hígado

Eisai

Publisher

Wiley

Subject

Hepatology

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