Composites of gellan gum hydrogel enzymatically mineralized with calcium-zinc phosphate for bone regeneration with antibacterial activity

Author:

Douglas Timothy E. L.1,Pilarz Magdalena2,Lopez-Heredia Marco3,Brackman Gilles4,Schaubroeck David5,Balcaen Lieve6,Bliznuk Vitaliy7,Dubruel Peter1,Knabe-Ducheyne Christine3,Vanhaecke Frank6,Coenye Tom4,Pamula Elzbieta2

Affiliation:

1. Polymer Chemistry and Biomaterials (PBM) Group, Department of Organic Chemistry; Ghent University; Belgium

2. Department of Biomaterials, Faculty of Materials Science and Ceramics; AGH University of Science and Technology; Krakow Poland

3. Department of Experimental and Orofacial Medicine, Faculty of Dentistry; Philipps University; Marburg Germany

4. Laboratory of Pharmaceutical Microbiology; Ghent University; Belgium

5. Centre for Microsystems Technology (CMST); IMEC, and Ghent University; Belgium

6. Department of Analytical Chemistry; Ghent University; Belgium

7. Department of Materials Science and Engineering; Zwijnaarde Belgium

Funder

Fonds Wetenschappelijk Onderzoek

Publisher

Wiley

Subject

Biomedical Engineering,Biomaterials,Medicine (miscellaneous)

Reference49 articles.

1. Alkaline phosphatase induces the mineralization of sheets of collagen implanted subcutaneously in the rat;Beertsen;J Clin Invest,1992

2. Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo;Brackman;Antimicrob Agents Chemother,2011

3. Benefits and drawbacks of zinc in glass ionomer bone cements;Brauer;Biomed Mater,2011

4. Aggregation and inhibition of rat intestinal alkaline phosphatase by high concentrations of calcium. Reversibility of the processes;Brun;J Enzyme Inhib Med Chem,2009

5. Novel bilayered gellan gum/gellan gum-hydroxyapatite scaffolds for osteochondral tissue engineering applications;Canadas;J Tissue Eng Regen Med,2012

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