Research and Application of Medical Polyetheretherketone as Bone Repair Material

Author:

Pu Feifei1ORCID,Yu Yihan2ORCID,Zhang Zhicai2,Wu Wei2,Shao Zengwu2,Li Chao2,Feng Jing1,Xue Longjian3,Chen Fengxia4

Affiliation:

1. Department of Orthopedics Traditional Chinese and Western Medicine Hospital of Wuhan (Wuhan No.1 Hospital) Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430022 China

2. Department of Orthopedics Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430022 China

3. School of Power and Mechanical Engineering Wuhan University Wuhan Hubei 430072 China

4. Department of Radiation and Medical Oncology Zhongnan Hospital Wuhan University Wuhan Hubei 430071 China

Abstract

AbstractPolyetheretherketone (PEEK) can potentially be used for bone repair because its elastic modulus is similar to that of human natural bone and good biocompatibility and chemical stability. However, its hydrophobicity and biological inertness limit its application in the biomedical field. Inspired by the composition, structure, and function of bone tissue, many strategies are proposed to change the structure and functionality of the PEEK surface. In this review, the applications of PEEK in bone repair and the optimization strategy for PEEK's biological activity are reviewed, which provides a direction for the development of multifunctional bone repair materials in the future.

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering,Biotechnology

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