Clinical outcomes of second‐line treatment following first‐line VEGFR‐TKI failure in patients with metastatic renal cell carcinoma: a comparison of axitinib alone and axitinib plus anti‐PD‐1 antibody

Author:

Huang Jiwei1ORCID,Wang Yueming1,Zhang Haoran2,Hu Xiaoyi3,Wang Ping4,Cai Wen5,Yuan Yichu5,Zeng Hao2,Zhang Jin1,Kong Wen1,Huang Yiran1,Wang Shuo4,Guo Jianming3,Wei Qiang2,Xue Wei1

Affiliation:

1. Department of Urology, Renji Hospital School of Medicine, Shanghai Jiao Tong University Shanghai 200127 P. R. China

2. Department of Urology West China Hospital, Sichuan University Chengdu Sichuan 610041 P. R. China

3. Department of Urology Zhongshan Hospital, Fudan University Shanghai 200032 P. R. China

4. Department of Urology First Affiliated Hospital, Zhejiang University School of Medicine Hangzhou Zhejiang 310003 P. R. China

5. Department of Urology Second Affiliated Hospital, Zhejiang University School of Medicine Hangzhou Zhejiang 310009 P. R. China

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference10 articles.

1. Systemic Therapy for Metastatic Renal-Cell Carcinoma

2. Pembrolizumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma

3. The 2021 Updated European Association of Urology Guidelines on Renal Cell Carcinoma: Immune Checkpoint Inhibitor‐based Combination Therapies for Treatment‐naive Metastatic Clear‐cell Renal Cell Carcinoma Are Standard of Care [published online ahead of print, 2021 May 29];Bedke J;Eur Urol,2021

4. Pembrolizumab (pembro) plusaxitinib (axi) versus sunitinib as first‐line therapy for metastatic renal cell carcinoma (mRCC): Outcomes in the combined IMDC intermediate/poor risk and sarcomatoid subgroups of the phase 3 KEYNOTE‐426 study;Brian R;J Clin Oncol.,2019

5. Cost Effectiveness of Nivolumab in Advanced Renal Cell Carcinoma

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