Affiliation:
1. Jilin Provincial Key Laboratory of Carbon Fiber Development and Application, College of Chemistry and Life Science, Advanced Institute of Materials Science Changchun University of Technology Changchun 130012 P.R. China
Abstract
AbstractNi‐catalyzed activation of C(sp2)−H bond remains an elusive challenge. Herein, we realized a Ni‐catalyzed selective activation of C(sp2)−H bond of formamides, which underwent addition reaction with internal alkynes to provide α,β‐unsaturated amide compounds in high yields. The protocol was featured by the cheap and nontoxic catalyst system. Preliminary mechanistic studies shed light on the reaction pathways.
Funder
National Natural Science Foundation of China