Affiliation:
1. Key Laboratory of New Low‐carbon Green Chemical Technology Education Department of Guangxi Zhuang Autonomous Region Guangxi Key Laboratory of Clean Pulp & Papermaking and Pollution Control School of Chemistry and Chemical Engineering School of Light Industry and Food Engineering Guangxi University Nanning China
2. CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety Institute of High Energy Physics Chinese Academy of Sciences Beijing China
Abstract
AbstractTwo‐dimensional Porphyrin‐based MOFs (2D p‐MOFs) and their derivatives have demonstrated significant potential in sensing and biomedical applications with their development and optimization expected to lead to significant advances in these fields. However, achieving a high quality of 2D p‐MOFs remains the present research rub and challenge. This review covers various methods and compound strategies for preparing 2D p‐MOFs including both bottom‐up and top‐down approaches, both of which have drawbacks that need to be addressed, and also summarizes their advantages for the obtained prepared 2D p‐MOF. Meanwhile, we review the different ways of functionalizing 2D porphyrin‐based MOF nanosheets with examples. It also highlights the crucial role of 2D p‐MOFs and derivatives in sensing applications, including food safety inspection, biomedical sensing, and environmental testing. Finally, the review summarizes the medical treatment based on 2D p‐MOFs, including drug delivery, photodynamic therapy (PDT), photothermal therapy, imaging, and more, further emphasizing the value of 2D p‐MOFs and derivatives.
Funder
National Natural Science Foundation of China