Therapy development in Huntington disease: From current strategies to emerging opportunities
Author:
Affiliation:
1. Departments of Neurology, Neurobiology, and Cell BiologyDuke Center for Neurodegeneration & NeurotherapeuticsDuke University Medical CenterDurhamNorth Carolina
Funder
National Institutes of Health
Publisher
Wiley
Subject
Genetics (clinical),Genetics
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajmg.a.38494
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1. Oral treatment with laquinimod augments regulatory T-cells and brain-derived neurotrophic factor expression and reduces injury in the CNS of mice with experimental autoimmune encephalomyelitis
2. A Huntingtin-based peptide inhibitor of caspase-6 provides protection from mutant Huntingtin-induced motor and behavioral deficits
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4. Quetiapine in the Treatment of Behavioral Disturbances in Patients With Huntington’s Disease
5. Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
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