Affiliation:
1. College of Chemistry, Chemical Engineering and Materials Science Soochow University Suzhou Jiangsu 215123 China
2. Physical Chemistry I & Research Center of Micro‐ and Nanochemistry and (Bio)Technology (Cμ), Department of Chemistry and Biology, School of Science and Technology University of Siegen Adolf‐Reichwein‐Str. 2 57076 Siegen Germany
Abstract
Comprehensive SummaryNanofluorophores based on aggregation‐induced emission (AIE) dyes have recently received considerable attention because of their unique optical properties and biocompatibility. In this work, we report an emission‐tunable nanofluorophore constructed by the self‐assembly of an amphiphilic block copolymer (denoted by PTN). The diblock copolymer was synthesized by RAFT polymerization. A polyethylene glycol‐based trithiocarbonate was employed as the macromolecular chain transfer agent, and a near‐infrared emitting tetraphenylethylene derivative with a vinyl terminal group was designed as the monomer. The block copolymers self‐assembled in an aqueous solution to form nanospheres, which showed near‐infrared emission at approximately 720 nm with a significant Stokes shift of approximately 260 nm. Furthermore, nanofluorophores have excellent biocompatibility, photostability, and pH‐independent emission‐tunable properties, and were successfully applied to label HeLa cells for fluorescence imaging.
Funder
Key University Science Research Project of Jiangsu Province
National Natural Science Foundation of China
Natural Science Foundation of Jiangsu Province