Appearance and recurrence of odontogenic keratocysts

Author:

Pylkkö Jaakko1,Willberg Jaana12,Suominen Auli3,Laine Hanna K.14,Rautava Jaana145ORCID

Affiliation:

1. Department of Oral Pathology and Oral Radiology, Institute of Dentistry, Faculty of Medicine University of Turku Turku Finland

2. Department of Pathology Turku University Central Hospital Turku Finland

3. Department of Community Dentistry University of Turku Turku Finland

4. Department of Oral and Maxillofacial Diseases, Clinicum, Faculty of Medicine University of Helsinki Helsinki Finland

5. Department of Pathology, HUS Diagnostic Center, HUSLAB Helsinki University Hospital Helsinki Finland

Abstract

AbstractObjectiveThe purpose of this study was to evaluate the appearance, histopathological features, and recurrence of odontogenic keratocysts (OKCs) from a large single institute registry over a 36‐year period.Materials and MethodsA total of 226 cases of OKC were identified in 174 patients over a 36‐year period in a single institute in Southwestern Finland. Histological specimens were re‐evaluated. The patient's age, sex, location, recurrence, and histopathological features of the OKC were the study variables.ResultsOKCs occurred more frequently in men, the mean age was 46 years, and the most frequent site was the lower jaw. Recurrence rate was 21%. Histopathologically, inflammation was present in 95% and satellite cysts in 10% of cases. In patients diagnosed with satellite cysts, OKC recurred in 50% of cases, while the corresponding figure for patients without satellite cysts was 17%.ConclusionsCompared with the literature, patients were older and inflamed cysts were found more frequently. Satellite cysts occurred only in association with chronic inflammation. Based on the results, regular radiographic evaluation is important among patients aged 10–29 years to detect OKCs and to treat them before enlargement, infection, and inflammation. Satellite cysts should be reported and may be a sign of increased risk of OKC recurrence.

Publisher

Wiley

Subject

General Dentistry

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