Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma
Author:
Affiliation:
1. Division of Toxicology, Leiden Academic Centre for Drug Research; Leiden University; The Netherlands
2. Department of Pathology; Leiden University Medical Centre (LUMC); The Netherlands
3. OcellO B.V. Leiden; The Netherlands
Publisher
Wiley
Subject
Pathology and Forensic Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/path.4528/fullpdf
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3. Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1;Chau;Mol Cell,2000
4. Aven blocks DNA damage-induced apoptosis by stabilising Bcl-xL;Kutuk;Eur J Cancer,2010
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