MiR-615-3p inhibits the osteogenic differentiation of human lumbar ligamentum flavum cells via suppression of osteogenic regulators GDF5 and FOXO1

Author:

Yin Jichao12,Zhuang Guihua1,Zhu Yi3,Hu Xinglv2,Zhao Hongmou3,Zhang Rongqiang4,Guo Hao3,Fan Xiaochen3,Cao Yi3

Affiliation:

1. Department of Epidemiology and Biostatistics; School of Public Health; Xi'an Jiaotong University Health Science Center; No. 76 West Yanta Road Xi'an Shaanxi 710061 China

2. Department of Orthopedics and Traumatology; Xi'an Hospital of Traditional Chinese Medicine; Xi'an China

3. Department of Traditional Chinese Medicine Orthopedics Diagnosis and Treatment Center; Xi'an Honghui Hospital; Xi'an China

4. Department of Public Health; Shaanxi University of Chinese Medicine; Xi'an China

Publisher

Wiley

Subject

Cell Biology,General Medicine

Reference29 articles.

1. Combinatorial signaling through BMP receptor IB and GD F5: shaping of the distal mouse limb and the genetics of distal limb diversity;Baur;Development,2000

2. Cyclic tensile strain facilitates the ossification of ligamentum flavum through β-catenin signaling pathway: in vitro analysis;Cai;Spine,2011

3. Origins and mechanisms of miRNAs and siRNAs;Carthew;Cell,2009

4. Mechanistic roles of leptin in osteogenic stimulation in thoracic ligament flavum cells;Fan;J Biol Chem,2007

5. Hormones and growth factors in the pathogenesis of spinal ligament ossification;Hai Li;Eur Spine J,2007

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