The content and effectiveness of physical activity for cancer‐related fatigue among colorectal cancer survivors: Systematic review and meta‐analysis

Author:

Geng Liangrong1ORCID,Li Xiaoyu1ORCID,Guo Liqun1,Zhang Rui1,Yue Shujin1ORCID

Affiliation:

1. School of Nursing Beijing University of Chinese Medicine Beijing China

Abstract

AbstractAimsTo review the content and efficacy of physical activity (PA) for cancer‐related fatigue (CRF) among colorectal cancer survivors.DesignSystematic review.MethodsA comprehensive search for randomized controlled trials from inception to April 1, 2022, of the following database was performed: EMBASE, PubMed, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Data and China Biology Medicine (CBM). RevMan5.4 software was used for performing meta‐analysis.ResultsA total of eight qualified randomized controlled trials that included 542 survivors were included. PA interventions significantly reduced the CRF (SMD = −0.46; 95% CI: [−0.76, −0.15], Z = 2.67, p = 0.003); Subgroup analysis showed that fatigue was significantly improved when the length of interventions was at least 6 months and the weekly duration of PA was less than 150 min/week (SMD = −0.54; 95% CI: [−0.81, −0.27], Z = 3.87 and p = 0.0001; SMD = −0.67; 95% CI: [−1.15, −0.19], Z = 2.74 and p = 0.006); PA intervention with the length of <6 months and the volume of ≥150 min/week did not reduce fatigue (p > 0.05).

Publisher

Wiley

Subject

General Nursing

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